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TED351586-2024

Notice of award - mIRage-LS, microscopy+nanospectroscopy platform for SDU

Oplyst værdi / estimat
821.684 EUR
Frist
Publiceret
14.6.2024
Leveringssted (NUTS)
DK031, DNK

Dataposten opdateret . Datakilder, dækning og beregningsmetode.

Tildeling

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Bekendtgørelsens samlede værdi: 821.684 EURKontrakt indgået: 11.6.2024
Registreringsnr. SE516411794601Oplyst værdi: 821.684 EUR

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Beskrivelse
Notice of award regarding purchase of a microscopy+nanospectroscopy platform, named mIRage-LS for SDU.

Procedure og udbudsmateriale

Oplysninger fra bekendtgørelsen kan dække flere delkontrakter. Listerne nedenfor er separate uddrag; rækkefølgen kobler ikke et kriterium til en beskrivelse eller delkontrakt. Kontrollér krav, vægtning, frister, optioner og eventuelle rettelser i originalmaterialet.

Proceduretype (kildens kode)

  • neg-wo-call

Beskrivelser af tildelingskriterier

  • The mIRage-LS is the first and only fully integrated and sample registration free combination of submicron IR, Raman and Fluorescence microscopy techniques combined into a single platform that heralds a breakthrough. Based on the periodic market research. The mIRage-LS utilizes Optical Photothermal Infrared (O-PTIR) spectroscopy technique with a visible probe to achieve top-down sub-micron IR illumination as standard. An optional bottom-up IR illumination design allows the use of high-power visible microscope collection objectives for significantly enhanced IR spatial resolution (<500nm). The integrated Raman spectrometer allows for simultaneous sub-micron IR and Raman spectroscopy and imaging at the same spot and at the same time with the same spatial resolution. The high-performance Fluorescence microscopy capability is also available, providing co-located IR and Fluorescence for fast localization of regions of interest for the IR measurement of bio-molecular structures. It is a critical instrument in advancing our understanding of nanoplastics, which have emerged as pressing environmental and health concerns. This state-of-the-art equipment fills significant knowledge gaps, particularly concerning nanosized particles (<1 µm), which have eluded detection due to limited methodologies. The mIRage-LS system's revolutionary capabilities enable rapid, automated detection, spectroscopic analysis, and chemical identification of these nano-sized pollutants, significantly enhancing our comprehension of their distribution, composition, and ecological impacts. Moreover, the mIRage- LS system is a powerful tool in safeguarding both environmental integrity and human well-being. Plastic particles have infiltrated aquatic ecosystems and have the potential to harm marine life and human health. The system's ability to identify the most biologically harmful plastic size fraction is invaluable for assessing environmental plastic pollution and its potential consequences. It empowers researchers to investigate the potential health risks associated with nanoplastics, helping to protect the environment and public health. The versatility and capacity of the mIRage-LS system, particularly including six unique advanced parts, is another compelling reason. The six advanced parts were meticulously selected to augment the capabilities of the mIRage-LS platform and advance our research. Each of these components is specifically tailored to enhance the automaticity, efficiency, accuracy, and overall capacity of the mIRage-LS platform within the context of our research project. This judicious allocation of resources is poised to contribute significantly to the success and impact of our project. The details of the six advanced add-ons are as follows. 1. LS-QCL-CH985: Upgrading the LS-QCL-03 mIRage HYPERspectra QCL Laser to cover (CHcore FP region) - (2990-2700 and 1800-985cm-1). This enhancement expands the spectral range, enabling comprehensive analysis of chemical functionalities of particles and molecular structures of cells within the specified regions. 2. UP-CP-ILLUM-LS: Transmission Illumination option for UP-CP-TRANS-LS. The mIRage-LS system comes standard with reflection mode optical illumination. This transmission illumination option allows us to optically observe a specimen with transmitted light below the specimen, providing improved contrast, especially for transparent samples like cells and transparent particles, contributing to a more accurate understanding of their biological interactions. 3. FLT-AFL-A: Filter Cube & Housing – Autofluorescence. Filter set for Autofluorescence 364. It provides excellent general-purpose autofluorescence imaging by exciting in the UV (355-375nm) and passing all emissions>425 nm, facilitating high-quality imaging of autofluorescence cellular structures. 4. FLT-XPOL-A: Microscopy Cube Cross Polarizer. It can minimize unwanted reflections and glare, improving image clarity, contrast, and precise morphological examination of our samples. 5. CHEMID-LS: featurefindIR microIR-Chemical ID Database. The featurefindIR microIR Chemical-ID is an integrated O-PTIR database that automatically analyzes all user-selected spectra within a PTIR Studio file, correlates them against a reference set of O-PTIR spectra in an integrated database, and provides a tabular output. The features enable automatic analysis and correlate user-selected spectra against a comprehensive reference set, facilitating efficient identification of chemical components of nanoplastics and biological samples, including: Import additional reference spectra from other sources; A hit quality index (HQI) is reported for every measured spectrum; An overlay is displayed between the measured and reference spectra; Color coding of common spectra is available for visual support; Includes common polymers plus spectra of common environmental interferents (e.g., cellulose, bone, protein, calcium carbonate, and sand). 6. UP-APD-LS: Ultra-Low Power Laser Detector. This detector enables mIRage-LS with 100x lower probe power than the standard visible detector while maintaining high IR sensitivity. It is especially useful for samples that are delicate, colored, dark, and strongly absorbing at the probe beam wavelength, significantly expanding the applicability of our research by allowing for a more comprehensive analysis of diverse and unknown sample types. This system will generate a comprehensive nanoplastic database accessible to different stakeholders in Denmark and beyond for understanding the plastic pollution issue and fostering innovative solutions and holistic strategies. Furthermore, the mIRage-LS system aligns with evolving regulations, such as those requiring plastic particle analysis in drinking water sources or foods. It equips research institutions to meet these regulatory demands effectively, ensuring compliance with environmental standards and providing reliable data to inform policy decisions.

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